Styrgruppen för odontologisk forskning

Projektbidrag 2025-2027

Efter vetenskaplig granskning av externa granskare och beslut av styrgruppen för odontologisk forskning har följande personer och projekt tilldelats SOF medel för 2025-2027:

• Abhishek Kumar: ”Breaking the Cycle: Phenotype Profiling in a Multidisciplinary Approach to Combat Age-Related Frailty and Malnutrition”

• Elisabeth Almer Boström: ”Oral manifestations in IBD: markers for prediction of inflammatory activity”

• Joannis Grigoriadis: ”Oral rehabilitation in patients with eating disorders”

• Maria Anderson: ”Evaluation of selective excavation and stepwise excavation in young permanent teeth with deep dental caries lesions (SELECT). A randomized controlled trial in a practice based research network”

• Mattias Ulmner: ”Surgical treatment of temporomandibular joint disc displacement: two randomised and controlled studies”

Projektbidrag 2024-2026

Efter vetenskaplig granskning av externa granskare och beslut av styrgruppen för odontologisk forskning har följande personer och projekt tilldelats SOF medel för 2024-2026:

• Anders Gustafsson: ”Early detection of oral cancer”

• Carina Kruger Weiner: ”AI, biomarkers, and precision medicine for prevention, diagnostics, and treatment of oral cancer”

• Bodil Lund: ”Deep neck infections and dental procedures”

• Angelika Silbereisen: ”Single-cell proteome and microbiome profiling of the oral mucosa in infectious and non-infectious diseases of oral soft tissues”

• Rachel Sugars: ”Clinical and diagnostic personalized management of patients with oral complications post-hematopoietic stem cell transplantation”

2023-2025

Projektbidrag 2023-2025

• Georgios Belibasakis: ”Surveillance of the oral resistome for life-threating oral infections”
• Kåre Buhlin: ”Dental disease and the impact on dementia risk and prognosis”
• Malin Ernberg: ”Is the kynurenine pathway upregulated in chronic muscle pain?”
• Mats Trulsson: ”Cognitive changes and neural correlates after rehabilitation of mastication in older adults – an intervention study”
• Tulay Yucel-Lindberg: ”Relationship of periodontitis and rheumatoid arthritis by microbiome and citrullination”

Projektbidrag junior 2023

• Ronaldo Lira Junior: ”Sex dimorphism in the behavior of oral neutrophils”

2022–2024

Forskningsprojekt som tilldelats anslag från SOF för perioden 2022–2024

• ”Molecular-based diagnostics for co-management of type 1 diabetes mellitus and oral health in an integrated personalized care approach”.
• ”Phenotype profiling of older individuals with chewing and swallowing problems with implications for clinical management of malnutrition”
• ”Developmental milestones to establish normality indicators of chewing function in children – From laboratory to clinic”
• ”Regenerative treatment of traumatized immature permanent incisors with pulp necrosis: A prospective multicenter study”
• ”Diagnostic and prognostic salivary biomarkers in chronic muscle pain”
• ”Validity and reliability of threedimensional measurement methods in dentistry” (2022–2023)
• ”Defining the functions of oral neutrophils in oral and systemic inflammation” (2022–2023)
• ”A case-management intervention aimed at reducing Early Childhood Caries in disadvantaged areas – a mixed methods study”. (2022–2023)

2020–2022

Forskningsprojekt som tilldelats anslag från SOF under perioden 2020–2022

1. Oral health in inflammatory bowel disease: pathogenic interplay and clinical utility for disease management. Principal investigator: Elisabeth Almér Boström.
2. Chair-side molecular diagnostics for oral antibiotic resistances in dental practice. Principal investigator: Georgios Belibasakis.
3. Investigation of periodontitis as contributor to risk of dementia: The MINOPAR project and beyond. Principal investigator: Kåre Buhlin.
4. The role of the kynurenine pathway and microbiota in chronic muscle pain. Principal investigator: Malin Ernberg.
5. Relationship of periodontitis and rheumatoid arthritis by oral microbiome and citrullination. Principal investigator: Tulay Lindberg.
6. Developing Clinical and Histopathology Models for Oral Lesion Diagnostics Using Artificial Intelligence. Principal investigator: Rachael Sugars.
7. Oral Cancer and Circulating Tumour-associated Molecules – A Network Integrative Approach to Improve Oral Cancer Diagnostics and Treatment. Principal investigator: Margaret Sällberg-Chen.
8. Cognitive changes and neural correlates after rehabilitation of mastication in older adults – an intervention study. Principal investigator: Mats Trulsson.

2019–2021

Forskningsprojekt som tilldelats anslag från SOF under perioden 2019–2021:

1. Modulation of macrophage function to improve periodontal health. Principal investigator: Elisabeth Almér Boström.
2. Down’s syndrome as a model for accelerating ageing to unravel drivers of periodontal ageing. Principal investigator: Nagihan Bostanci.
3. A telephone-based case-management intervention for caries prevention in children with severe early childhood caries before 3 years of age. Principal investigator: Göran Dahllöf.
4. Significance of molecular biomarkers for the pathogenesis of temporomandibular disorders myalgia. Principal investigator: Malin Ernberg.
5. Prediction of disease activity and temporomandibular joint involvement in patients with juvenile idiopathic arthritis. Principal investigator: Britt Hedenberg-Magnusson.
6. Antibiotic stewardship in odontology. Principal investigator: Bodil Lund.
7. Oral microbiota in pancreatic cancer development and immune surveillance. Principal investigator: Margaret Sällberg-Chen.
8. Oral Graft-Versus-Host Disease: Clinical and Artificial Intelligence-Driven Pathological Diagnostics. Principal investigator: Rachael Sugars.
9. Prospective studies for identifying sensorimotor impairment and optimizing chewing function in the elderly population. Principal investigator: Mats Trulsson.
10. Domicillary professional oral care for dependent elderly – a continuing project and extended application. Principal investigator: Inger Wårdh.